Indications for surgery in Infective Endocarditis; ABCVE

AAbscess of valve
BBacteremia, Persistent [BC positive after 6 days while on antibiotics]
CCHF, new and severe
VVegetation, large fungal
EEmboli, recurrent

Cephalosporins do not cover Enterococci.

Do weekly CK if Daptomycin is used. Daptomycin is not used for pneumonia as its deactivated by surfactant.

Tigecycline does not go into urine so we dont use for UTI. It goes into bile.

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