Renal Tubular Acidosis 241

Renal tubular acidosis (RTA) occurs when the kidneys do not remove acids from the blood into the urine as they should.

Type 3 RTA is rarely used as a classification because it’s thought to be a combination of type 1 and type 2 RTA. [3=1+2]

We need to be thorough with these 3 types of Renal Tubular Acidosis.

RTA type241
LocationProximalHyperkalemicDistal
DefectHCO3
reabsorption
H,K
excretion
H
excretion
HypokalemiaHyperKalemiaHypokalemia
Stones +/- +
pH>5.5 <5.5
Conditions
Tip to rememberTWO
TOMAF
HK and HDONE
OPRASSH
TopiramateHypoaldosteronismObstruction [distal]
OsteomalaciaDiabetes MellitusPBC
Multiple MyelomaRA
Acetazolamide/ZonisamideAmphotericin
Fanconi SyndromeSLE
Sjogren’s
Hyperthyroidism
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